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N-Desethylisotonitazene (norisotonitazene) is a benzimidazole opioid with potent analgesic effects which has been sold as a designer drug.It was first identified in 2023 as an active metabolite of the closely related compound isotonitazene, and was found to have similar potency.
Norbinaltorphimine (nor-BNI or nBNI) is an opioid antagonist used in scientific research. It is one of the few opioid antagonists available that is highly selective for the κ-opioid receptor, and blocks this receptor without affecting the μ-or δ-opioid receptors, [2] [3] although it is less selective in vivo than in isolated tissues.
Tianeptine/naloxone (developmental code names TNX-601, TNX-601-CR, TNX-601-ER), or naloxone/tianeptine, is an extended-release combination of tianeptine, an atypical μ-opioid receptor agonist, and naloxone, an orally inactive μ-opioid receptor antagonist, which was under development for the treatment of major depressive disorder, post-traumatic stress disorder (PTSD), and neurocognitive ...
The information presented in this map reflects the results of hospice inspections provided by the Centers for Medicare and Medicaid Services (CMS), the hospice industry’s federal regulator, in response to a public records request. The time period covers Jan. 2, 2004, to Oct. 16, 2014.
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24/7 Help. For premium support please call: 800-290-4726 more ways to reach us. Mail. Sign in. Subscriptions; ... December 17, 2024 at 1:00 PM. 100+ Best-Ever Christmas Desserts Bryan Gardner
One of the busiest travel days of the year got off to a rough start due to a "technical issue" that disrupted American Airlines flights across the U.S.