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  2. Orexin antagonist - Wikipedia

    en.wikipedia.org/wiki/Orexin_antagonist

    An orexin receptor antagonist, or orexin antagonist, is a drug that inhibits the effect of orexin by acting as a receptor antagonist of one (selective orexin receptor antagonist or SORA) or both (dual orexin receptor antagonis or DORA) of the orexin receptors, OX 1 and OX 2. [1] Medical applications include treatment of sleep disorders such as ...

  3. Hypnotic - Wikipedia

    en.wikipedia.org/wiki/Hypnotic

    Zolpidem tartrate, a common but potent sedativehypnotic drug.Used for severe insomnia. Hypnotic (from Greek Hypnos, sleep [1]), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep [2] (or surgical anesthesia [note 1]) and to treat insomnia (sleeplessness).

  4. Sedative - Wikipedia

    en.wikipedia.org/wiki/Sedative

    Because these two functions frequently overlap, and because drugs in this class generally produce dose-dependent effects (ranging from anxiolysis to loss of consciousness) they are often referred to collectively as sedative-hypnotic drugs. [4] Sedatives can be used to produce an overly calming effect (alcohol being the most common sedating drug ...

  5. Somnifacient - Wikipedia

    en.wikipedia.org/wiki/Somnifacient

    Somnifacient (from Latin somnus, sleep [1]), also known as sedatives or sleeping pills, is a class of medications that induces sleep. It is mainly used for treatment of insomnia. Examples of somnifacients include benzodiazepines, barbiturates and antihistamines. Around 2-6% of adults with insomnia use somnifacients to aid sleep. [2]

  6. Alprazolam - Wikipedia

    en.wikipedia.org/wiki/Alprazolam

    Side effects from alprazolam. Sedative drugs, including alprazolam, have been associated with an increased risk of death. [35] Possible side effects include: Anterograde amnesia [36] Concentration problems; Ataxia; Dysarthria [37] Disinhibition [38] Drowsiness, dizziness, lightheadedness, fatigue, ataxia, and vertigo [39] [40] Dry mouth ...

  7. Mirtazapine - Wikipedia

    en.wikipedia.org/wiki/Mirtazapine

    Mirtazapine is a very strong H 1 receptor antagonist and, as a result, it can cause powerful sedative and hypnotic effects. [11] A single 15 mg dose of mirtazapine to healthy volunteers has been found to result in over 80% occupancy of the H 1 receptor and to induce intense sleepiness. [92]

  8. Hydroxyzine - Wikipedia

    en.wikipedia.org/wiki/Hydroxyzine

    The use of sedating drugs alongside hydroxyzine can cause oversedation and confusion if administered at high doses—any form of hydroxyzine treatment alongside sedatives should be done under the supervision of a doctor. [28] [25] Because of the potential for more severe side effects, this drug is on the list to avoid in the elderly. [29]

  9. Diazepam - Wikipedia

    en.wikipedia.org/wiki/Diazepam

    Diazepam increases the central depressive effects of alcohol, other hypnotics/sedatives (e.g., barbiturates), other muscle relaxants, certain antidepressants, sedative antihistamines, opioids, and antipsychotics, as well as anticonvulsants such as phenobarbital, phenytoin, and carbamazepine. The euphoriant effects of opioids may be increased ...