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Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that are expressed and secreted by white blood cells (leukocytes) as well as some other body cells. The human genome encodes more than 50 interleukins and related proteins.
Interleukin 17 family (IL17 family) is a family of pro-inflammatory cystine knot cytokines. [2] They are produced by a group of T helper cell known as T helper 17 cell in response to their stimulation with IL-23.
16183 Ensembl ENSG00000109471 ENSMUSG00000027720 UniProt P60568 P04351 RefSeq (mRNA) NM_000586 NM_008366 RefSeq (protein) NP_000577 NP_032392 Location (UCSC) Chr 4: 122.45 – 122.46 Mb Chr 3: 37.17 – 37.18 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin-2 (IL-2) is an interleukin, which is a type of cytokine signaling molecule forming part of the immune system. It is a ...
IL-1 family is a group of 11 cytokines, which induces a complex network of proinflammatory cytokines and via expression of integrins on leukocytes and endothelial cells, regulates and initiates inflammatory responses.
T h 17 cells produce interleukin 17 (IL-17), a pro-inflammatory substance, as well as interleukins 21 and 22. [26] This means that T h 17 cells are especially good at fighting extracellular pathogens [ 26 ] and fungi, particularly during mucocutaneous immunity against Candida spp. [ 27 ]
Interleukins are another class of cytokine signaling molecules important in hemopoiesis. They were initially thought to be secreted uniquely by leukocytes and to communicate only with other leukocytes, and were named accordingly, but are now known to be produced by a variety of cells including bone marrow and endothelium.
Interleukin 3 is an interleukin, a type of biological signal that can improve the body's natural response to disease as part of the immune system. [10] In conjunction with other β common chain cytokines GM-CSF and IL-5, IL-3 works to regulate the inflammatory response in order to clear pathogens by changing the abundance of various cell populations via binding at the interleukin-3 receptor.
16196 Ensembl ENSG00000104432 ENSMUSG00000040329 UniProt P13232 P10168 RefSeq (mRNA) NM_000880 NM_001199886 NM_001199887 NM_001199888 NM_008371 NM_001313888 NM_001313889 NM_001313890 RefSeq (protein) NP_000871 NP_001186815 NP_001186816 NP_001186817 NP_001300817 NP_001300818 NP_001300819 NP_032397 Location (UCSC) Chr 8: 78.68 – 78.81 Mb Chr 3: 7.64 – 7.68 Mb PubMed search Wikidata View/Edit ...