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In general, patients with acute ITP will only rarely have life-threatening bleeding. [54] Most patients ultimately have lower, but stable platelet counts, which are still hemostatic for the patient. Unlike children and adolescents, ITP is often chronic in adults, even after a splenectomy. [40]
Schwartz notes that the Harrington–Hollingsworth experiment was a turning point in the understanding of ITP's pathophysiology: The Harrington–Hollingsworth experiment changed the meaning of the "I" in ITP from idiopathic to immune, but "immune" in this case means "autoimmune," because the antibodies bind to and cause the destruction of the patient's own platelets.
Process for screening and diagnosing ASD; M-CHAT is Modified Checklist for Autism in Toddlers; (+) is positive test result; (−) is negative test result. There are several factors that make autism spectrum disorder difficult to diagnose. First off, there are no standardized imaging, molecular or genetic tests that can be used to diagnose ASD. [4]
The Childhood Autism Spectrum Test, abbreviated as CAST and formerly titled the Childhood Asperger Syndrome Test, is a tool to screen for autism spectrum disorder in children aged 4–11 years, in a non-clinical setting. [1] It is also called the Social and Communication Development Questionnaire. [2]
The autism-spectrum quotient (AQ) is a questionnaire published in 2001 by Simon Baron-Cohen and his colleagues at the Autism Research Centre in Cambridge, UK.Consisting of fifty questions, it aims to investigate whether adults of average intelligence (defined as an IQ of 80 or higher by the questionnaire) have symptoms of autism spectrum conditions. [1]
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The Autism Diagnostic Observation Schedule (ADOS) is a standardized diagnostic test for assessing autism spectrum disorder.The protocol consists of a series of structured and semi-structured tasks that involve social interaction between the examiner and the person under assessment.
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