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  2. CRISPR - Wikipedia

    en.wikipedia.org/wiki/CRISPR

    The CRISPR array is made up of an AT-rich leader sequence followed by short repeats that are separated by unique spacers. [79] CRISPR repeats typically range in size from 28 to 37 base pairs (bps), though there can be as few as 23 bp and as many as 55 bp. [ 80 ] Some show dyad symmetry , implying the formation of a secondary structure such as a ...

  3. Intellia Therapeutics - Wikipedia

    en.wikipedia.org/wiki/Intellia_Therapeutics

    In June 2021, Intellia made history by announcing interim Phase 1 data for NTLA-2001, demonstrating the ability to precisely edit target cells within the body to treat genetic disease with a single intravenous infusion of CRISPR. This was the first time any human clinical data has been published for an in vivo gene editing therapeutic candidate.

  4. Yoshizumi Ishino - Wikipedia

    en.wikipedia.org/wiki/Yoshizumi_Ishino

    As the DNA segment used was longer than the gene itself, they accidentally discovered a partial DNA sequence of then-unnamed CRISPR in the process, [7] which would eventually become the basis of CRISPR gene editing. Ishino was one of the first scientists to have detected CRISPRs in E. coli. [8] In 1990, Ishino began researching DNA replication ...

  5. CRISPR gene editing - Wikipedia

    en.wikipedia.org/wiki/CRISPR_gene_editing

    In 2012 and 2013, CRISPR was a runner-up in Science Magazine's Breakthrough of the Year award. In 2015, it was the winner of that award. [ 198 ] CRISPR was named as one of MIT Technology Review ' s 10 breakthrough technologies in 2014 and 2016.

  6. 2 Biotech Stocks That Are Screaming Buys This Month - AOL

    www.aol.com/2-biotech-stocks-screaming-buys...

    CRISPR Therapeutics recently hit a breakthrough point when it earned approval for its first product, Casgevy, a therapy for sickle cell disease and transfusion-dependent beta-thalassemia.

  7. Mammoth Biosciences - Wikipedia

    en.wikipedia.org/wiki/Mammoth_Biosciences

    Mammoth signed agreements in December 2019 and January 2020 with Horizon Discovery to combine Mammoth's intellectual property in CRISPR with Horizon's expertise in Chinese hamster ovary cells. [5] Also in 2020, both Mammoth Biosciences and Sherlock Biosciences from the Broad Institute used their similar CRISPR technologies to develop tests for ...

  8. Kim Jin-soo (biologist) - Wikipedia

    en.wikipedia.org/wiki/Kim_Jin-soo_(biologist)

    CRISPR-Cas9 is a widely used genetic tool but testing its accuracy genome wide is difficult. [6] In 2015, Kim's IBS Center, Seoul National University, and ToolGen jointly published a paper in Nature Methods outlining their technique named Digenome-seq which locates on-target and off-target sequences in CRISPR-Cas9. [ 7 ]

  9. 1 big new Green Flag for CRISPR Therapeutics' Stock - AOL

    www.aol.com/finance/1-big-green-flag-crispr...

    CRISPR Therapeutics (NASDAQ: CRSP) isn't a stock that's wanting for reasons to invest. Per the company's presentation at the American Society of Hematology's (ASH) annual meeting on Dec. 9, the ...