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Streptococcal pharyngitis, also known as streptococcal sore throat (strep throat), is pharyngitis (an infection of the pharynx, the back of the throat) caused by Streptococcus pyogenes, a gram-positive, group A streptococcus. [9] [10] Common symptoms include fever, sore throat, red tonsils, and enlarged lymph nodes in the front of the neck.
Group A streptococcal infections are a number of infections with Streptococcus pyogenes, a group A streptococcus (GAS). [1] S. pyogenes is a species of beta-hemolytic Gram-positive bacteria that is responsible for a wide range of infections that are mostly common and fairly mild. If the bacteria enters the bloodstream, the infection can become ...
Chains of S. pyogenes bacteria (orange) at 900× magnification Gram stain of Streptococcus pyogenes. Unlike most bacterial pathogens, S. pyogenes only infects humans. Thus, zoonotic transmission from an animal (or animal products) to a human is rare. [8] S. pyogenes typically colonizes the throat, genital mucosa, rectum, and skin. Of healthy ...
Similarly, group B streptococcus typically denotes Streptococcus agalactiae, although minor beta-hemolytic group B streptococci like S. troglodytidis exist. [15] While most streptococcal illnesses in humans originate from species adapted to humans, such as S. pneumoniae or S. pyogenes, there are zoonotic species capable of causing infections. [15]
A case of strep throat. Streptococcal pharyngitis or strep throat is caused by a group A beta-hemolytic streptococcus (GAS). [20] It is the most common bacterial cause of cases of pharyngitis (15–30%). [19] Common symptoms include fever, sore throat, and large lymph nodes. It is a contagious infection, spread by close contact with an infected ...
The rapid strep test (RST) is a rapid antigen detection test (RADT) that is widely used in clinics to assist in the diagnosis of bacterial pharyngitis caused by group A streptococci (GAS), sometimes termed strep throat. There are currently several types of rapid strep test in use, each employing a distinct technology.
M protein is strongly anti-phagocytic and is the major virulence factor for group A streptococci (Streptococcus pyogenes). It binds to serum factor H, destroying C3-convertase and preventing opsonization by C3b. However plasma B cells can generate antibodies against M protein which will help in opsonization and further the destruction of the ...
A 2015 study of young adult students presenting to a single clinic in Alabama had F. necrophorum as the predominant causative organism for pharyngitis 21% of the time (and found in 9% of asymptomatic students). [11] In the same study, Group A Streptococcus was found in 10% of pharyngitis patients (1% of asymptomatic students).