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Summation, which includes both spatial summation and temporal summation, is the process that determines whether or not an action potential will be generated by the combined effects of excitatory and inhibitory signals, both from multiple simultaneous inputs (spatial summation), and from repeated inputs (temporal summation).
A neuromuscular junction (or myoneural junction) is a chemical synapse between a motor neuron and a muscle fiber. [1] It allows the motor neuron to transmit a signal to the muscle fiber, causing muscle contraction. [2] Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy.
In neurophysiology, the Compound action potential (or CAP) refers to various evoked potentials representing the summation of synchronized individual action potentials generated by a group of neurons or muscle fibers in response to a stimulus. [1]
The compound muscle action potential (CMAP) or compound motor action potential is an electrodiagnostic medicine investigation (electrical study of muscle function). The CMAP idealizes the summation of a group of almost simultaneous action potentials from several muscle fibers in the same area.
The summation of these three EPSPs generates an action potential. In neuroscience , an excitatory postsynaptic potential ( EPSP ) is a postsynaptic potential that makes the postsynaptic neuron more likely to fire an action potential .
Signal transmission from nerve to muscle at the motor end plate. The neuromuscular junction is the synapse that is formed between an alpha motor neuron (α-MN) and the skeletal muscle fiber. In order for a muscle to contract, an action potential is first propagated down a nerve until it reaches the axon terminal of the motor neuron.
Central sensitization of the dorsal horn neurons that is evoked from C fiber activity is responsible for temporal summation of "second pain" (TSSP). [15] This event is called 'windup' and relies on a frequency greater or equal to 0.33 Hz of the stimulus. [15] Windup is associated with chronic pain and central sensitization. [15]
Summation is the adding together of these impulses at the axon hillock. If the neuron only gets excitatory impulses, it will generate an action potential. If the neuron only gets excitatory impulses, it will generate an action potential.