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The most common area of involvement is the cortical white matter of frontal and parieto occipital lobes, but lesions may occur anywhere in the brain, such as the basal ganglia, external capsule, and posterior cranial fossa structures such as the brain stem and cerebellum. [12]
These small regions of high intensity are observed on T2 weighted MRI images (typically created using 3D FLAIR) within cerebral white matter (white matter lesions, white matter hyperintensities or WMH) [1] [2] or subcortical gray matter (gray matter hyperintensities or GMH). The volume and frequency is strongly associated with increasing age. [2]
Leukoencephalopathy (leukodystrophy-like diseases) is a term that describes all of the brain white matter diseases, whether their molecular cause is known or unknown. [1] It can refer specifically to any of these diseases: Progressive multifocal leukoencephalopathy; Toxic leukoencephalopathy
Transcortical motor aphasia (TMoA), also known as commissural dysphasia or white matter dysphasia, results from damage in the anterior superior frontal lobe of the language-dominant hemisphere. This damage is typically due to cerebrovascular accident (CVA).
Cerebral white-matter lesions; Cause. Porencephaly is a rare disorder. ... Cysts can develop in the frontal lobe, parietal lobe, forebrain, hindbrain, ...
Researchers collected MRI data to evaluate brain white matter health and microstructure, with analysis focusing on white matter volume, lesion volume and quantification of white matter ...
Evidence from subcortical small infarcts suggests that motor fibers are somatotopically arranged in the human corona radiata. Following subtotal brain damage, localization of the corticofugal projection in the corona radiata and internal capsule can assist in evaluating a patient's residual motor capacity and predicting their potential for functional restitution.
The lobes of the brain most likely to be injured are the frontal and temporal lobes. [19] Other common locations for DAI include the white matter in the cerebral cortex , the superior cerebral peduncles , [ 16 ] basal ganglia , thalamus , and deep hemispheric nuclei.