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Side effects include skin flushing, shortness of breath, fever, and red blood cell breakdown. [12] [13] Allergic reactions including anaphylaxis may occur. [13] It is unclear if use during pregnancy is safe for the fetus. [14] A purified factor VIII concentrate is made from human blood plasma. [13] A recombinant version is also available. [12]
Marstacimab, sold under the brand name Hympavzi, is a monoclonal antibody medication used for the treatment of hemophilia A and hemophilia B. [1] [4] [2] It is a tissue factor pathway inhibitor (TFPI) antagonist. [4] It was developed by Pfizer. [5]
The most common side effects with Cevenfacta include injection site discomfort and hematoma (a collection of blood under the skin) as well as injection-related reactions, an increase in body temperature, dizziness and headache. [5] Novoseven was approved for medical use in the European Union in February 1996, [4] and in the United States in ...
Damoctocog alfa pegol, sold under the brand name Jivi is a recombinant DNA-derived, Factor VIII concentrate used to treat hemophilia A. [5] [6] The most common side effects include headache, cough, nausea, and fever. [5] Damoctocog alfa pegol was approved for medical use in the United States in August 2018, [7] and in the European Union in ...
Hympavzi is the first and only anti-tissue factor pathway inhibitor (anti-TFPI) approved in the U.S. for hemophilia A or B and the first hemophilia medicine approved in the U.S. to be administered via
Concizumab, sold under the brand name Alhemo, is a monoclonal antibody used for the treatment of hemophilia A and hemophilia B. [5] [8] It is an anti-tissue factor pathway inhibitor. [5] [8] The most common adverse reactions include injection site reactions and hives (urticaria). [11]
There’s a new one-time treatment for Hemophilia B patients in the market, but it comes with an obscene price tag. A hemophilia drug that just won FDA approval pegs a one-time $3.5 million vial ...
Prothrombin complex concentrate (PCC), also known as factor IX complex, sold under the brand name Kcentra among others, is a combination medication made up of blood clotting factors II, IX, and X [9] (3-factor PCC) or, when also containing factor VII as does Kcentra, 4-factor PCC. [10]
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