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Comm expression turns off after the growth cone has crossed the midline; this permits Robo/Slit repulsion and prevents the growth cone from crossing the midline again. Vertebrates, on the other hand, do not possess a comm homolog ; instead they facilitate midline crossing through alternative splicing of Robo3 (aka.Rig-1).
This article is about the optic chiasm of vertebrates, which is the best known nerve chiasm, but not every chiasm denotes a crossing of the body midline (e.g., in some invertebrates, see Chiasm (anatomy)). A midline crossing of nerves inside the brain is called a decussation (see Definition of types of crossings).
In mammals and birds and other vertebrates with frontal eyes, the optic nerves do blend in the optic chiasm, and only part of the nerve fibres cross the midline. [5] The drawings of Cajal suggest that the axons of the optic nerve may branch in the optic chiasm, and thus give off a branch both in the ipsi- and contralateral optic tract. [ 5 ]
The anterior commissure (also known as the precommissure) is a tract that connects the two temporal lobes of the cerebral hemispheres across the midline, and placed in front of the columns of the fornix.
It is still uncertain whether the interthalamic adhesion contains fibers that cross the midline – and for this reason, it is inappropriate to call it a commissure. The interthalamic adhesion is notably enlarged in patients with the type II Arnold–Chiari malformation .
The lateral corticospinal tract neurons cross the midline at the level of the medulla oblongata, and controls the limbs and digits. [1] [3] The lateral tract forms about 90% of connections in the corticospinal tract; [2] the vast majority cross over in the medulla, while the rest (about 2-3%) remain ipsilateral. The anterior corticospinal tract ...
These fibers cross the midline and ascend to the contralateral thalamus. The dorsal trigeminal tract - consists of second-order axons from the principal sensory nucleus of trigeminal nerve. These fibers do not cross the midline, and ascend to the ipsilateral thalamus.
Decussation is used in biological contexts to describe a crossing (due to the shape of the Roman numeral for ten, an uppercase 'X' , from Latin decem 'ten' and as 'as'). In Latin anatomical terms, the form decussatio is used, e.g. decussatio pyramidum. Similarly, the anatomical term chiasma is named after the Greek uppercase 'Χ' .
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