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  2. 2,4-Dinitrophenol - Wikipedia

    en.wikipedia.org/wiki/2,4-Dinitrophenol

    In humans, DNP causes dose-dependent mitochondrial uncoupling, causing the rapid loss of ATP as heat and leading to uncontrolled hyperthermia—up to 44 °C (111 °F)—and death in case of overdose. Researchers noticed its effect on raising the basal metabolic rate in accidental exposure and developed it as one of the first weight loss drugs ...

  3. What is DNP and why is it so dangerous? - AOL

    www.aol.com/dnp-why-dangerous-140847464.html

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  4. Anti-obesity medication - Wikipedia

    en.wikipedia.org/wiki/Anti-obesity_medication

    Overdose caused fatal hyperthermia and DNP also caused cataracts in some users. After the passage of the Food, Drug, and Cosmetic Act in 1938, the FDA banned DNP for human consumption. [37] Amphetamines (marketed as Benzedrine) became popular for weight loss during the late 1930s. They worked primarily by suppressing appetite, and had other ...

  5. Nordazepam - Wikipedia

    en.wikipedia.org/wiki/Nordazepam

    Nordazepam is among the longest lasting (longest half-life) benzodiazepines, and its occurrence as a metabolite is responsible for most cumulative side-effects of its myriad of pro-drugs when they are used repeatedly at moderate-high doses; the nordazepam metabolite oxazepam is also active (and is a more potent, full BZD-site agonist), which ...

  6. One small thing can add years to your life, experts say - AOL

    www.aol.com/news/one-small-thing-add-years...

    Editor’s note: One Small Thing is a new series to help you take a simple step toward a healthy, impactful goal. Try this one thing, and you’ll be heading in the right direction.

  7. How Much Should You Exercise on Ozempic? - AOL

    www.aol.com/much-exercise-ozempic-135700374.html

    Wegovy, a higher-dose version of semaglutide, was approved in 2021 for weight loss in people with obesity or overweight with obesity-related conditions like high blood pressure (hypertension) and ...

  8. Natriuretic peptide - Wikipedia

    en.wikipedia.org/wiki/Natriuretic_peptide

    Natriuretic peptides and their receptors have many different effects on the body, such as controlling blood pressure and helping bones grow. Each peptide has its own unique effects and interacts with specific receptors. Scientists have observed these effects by studying mice with specific natriuretic peptides or receptors removed. [3]

  9. Cenderitide - Wikipedia

    en.wikipedia.org/wiki/Cenderitide

    Cenderitide (also known as chimeric natriuretic peptide or CD-NP) is a natriuretic peptide developed by the Mayo Clinic as a potential treatment for heart failure. [1] [2] [3] Cenderitide is created by the fusion of the 15 amino acid C-terminus of the snake venom dendroaspis natriuretic peptide (DNP) with the full C-type natriuretic peptide (CNP) structure. [2]